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Acheter Modafinil En Suisse
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Les résultats suggèrent qu'après quatre semaines de traitement avec 100 à 200 mg de Modafinil chez des volontaires sains le soir et la nuit, il y a eu une réduction significative de la somnolence et une augmentation des performances psychomotrices. Les comprimés de modafinil, disponibles sous le nom de marque Provigil et vendus sous la forme de 90 ou 150 mg de modafinil par comprimé, sont classés comme substance contrôlée de l'annexe IV aux États-Unis. Il modifie également la production de gènes spécifiques dans les cellules impliquées dans le comportement et la production d'hormones, affectant la sensibilité à la noradrénaline et à la sérotonine. Le modafinil diffère de la plupart des antidépresseurs (et même des autres stimulants du SNC) en ce qu'il ne semble pas inhiber le transporteur de la sérotonine et que son action n'est pas médiée par les IMAO. Le modafinil est un médicament racémique avec un rapport énantiomérique d'environ 1 pour 1. Acheter Modafinil En Suisse Le modafinil n'est pas approuvé pour être utilisé comme activateur cognitif. Le mécanisme d'action n'est pas entièrement compris, mais on pense qu'il augmente l'éveil en stimulant le cortex préfrontal du cerveau. Le modafinil a une très longue demi-vie (28 heures), suggérant que des doses élevées pourraient être prises de façon régulière sans devoir être prises à fortes doses. Il est préférable de les prendre au moins deux heures avant le coucher. On sait peu de choses sur le fonctionnement du modafinil dans le cerveau. Le modafinil est métabolisé en N-desméthyl modafinil. Le modafinil est connu pour inhiber la recapture de ces neurotransmetteurs. On ne sait pas exactement comment Modafinil fonctionne. Le modafinil présente un risque de convulsions, principalement chez les personnes ayant des antécédents de psychose ou de trouble bipolaire ou chez celles qui prennent du valproate ou de la phénytoïne. Bien qu'il ait été utilisé hors AMM comme prétendu activateur cognitif pour améliorer l'éveil dans des études animales et humaines, la recherche sur son efficacité pour cette utilisation n'est pas concluante. Le modafinil a reçu l'approbation pour une utilisation comme activateur cognitif aux États-Unis en 1998. En 1990, une équipe dirigée par des chercheurs de l'Université du Kansas a publié un article dans Dormir faire des revendications similaires.
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