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Par consГ©quent, il aide Г stimuler les neurones et les cellules nerveuses du cerveau. Il n'est pas recommandГ© de l'utiliser avec d'autres mГ©dicaments ayant un mode d'action similaire. Les personnes doivent ГЄtre surveillГ©es si elles ont une maladie cardiaque ou des antГ©cГ©dents de psychose. Le modafinil agit Г©galement en antagonisant l'action de l'histamine. Les chercheurs ont suggГ©rГ© que le modafinil pourrait ГЄtre utile dans le traitement de plusieurs troubles, notamment le TDAH, la narcolepsie et l'apnГ©e du sommeil, mais son utilitГ© n'a pas encore Г©tГ© Г©tablie. Il a Г©tГ© observГ© que le modafinil module les rГ©cepteurs dopaminergiques dans le cortex frontal, une zone du cerveau associГ©e Г la vigilance et Г l'Г©veil. Bien que le modafinil puisse avoir des avantages Г court terme, les effets secondaires, les risques et les avantages Г long terme sont inconnus. L'utilisation de modafinil peut augmenter la dГ©pression et l'anxiГ©tГ©. Il contient 200 mg de modafinil. L'activation des rГ©cepteurs D2 entraГ®ne une accumulation de sГ©rotonine, de sorte que le modafinil augmente la dopamine en augmentant la libГ©ration de sГ©rotonine. Le modafinil agit comme un stimulant sГ©lectif et puissant du systГЁme nerveux central (SNC), mais n'affecte pas la rГ©gulation de la sГ©rotonine, de l'acГ©tylcholine (ACh) ni de la dopamine. Le modafinil est disponible sous forme de comprimГ© oral, de comprimГ© Г libГ©ration modifiГ©e et de liquide. Ils ont dГ©couvert que cela Г©tait dГ» en partie Г un effet stimulant sur l'activitГ© dopaminergique. Le modafinil peut Г©galement augmenter la sensation de vigilance pendant l'Г©veil. Il a Г©tГ© homologuГ© en France en janvier 1994 pour les somnolences diurnes excessives associГ©es Г la narcolepsie. provigil france En plus de cela, les mГ©dicaments WEEA peuvent ГЄtre en mesure d'augmenter l'effet de l'alcool, car ils peuvent prГ©venir les effets sГ©datifs de l'alcool. Des Г©tudes animales rГ©centes ont rГ©vГ©lГ© que ses propriГ©tГ©s apparentes d'amГ©lioration de la cognition peuvent ne pas ГЄtre le rГ©sultat d'effets d'amГ©lioration directs sur l'activitГ© corticale, mais peuvent plutГґt reflГ©ter sa capacitГ© Г amГ©liorer la rГ©cupГ©ration aprГЁs l'apprentissage et les troubles cognitifs induits par le stress. Le modafinil a Г©tГ© qualifiГ© de "mГ©dicament intelligent" en raison de la quantitГ© limitГ©e d'informations disponibles sur son mГ©canisme. Aucun mГ©dicament connu ne peut rivaliser avec le pouvoir du Modafinil pour stimuler l'Г©veil. L'amГ©lioration cognitive (l'utilisation d'un mГ©dicament pour stimuler la cognition) est devenue un sujet de discussion populaire. Le modafinil agit Г©galement comme un modulateur allostГ©rique positif du rГ©cepteur muscarinique de l'acГ©tylcholine M1, qui peut Г©galement contribuer Г certaines de ses actions. C'est un traitement des troubles du sommeil tels que la narcolepsie et les troubles du sommeil liГ©s au travail postГ©. Le modafinil est Г©galement utilisГ© Г fortes doses pour augmenter l'Г©veil chez les personnes souffrant d'apnГ©e du sommeil. En fait, le modafinil est un mГ©dicament stimulant qui est probablement mieux comparГ© au mГ©thylphГ©nidate stimulant sur ordonnance pour le TDAH, et comme le mГ©thylphГ©nidate, il est le plus efficace comme traitement de la somnolence chez les travailleurs postГ©s. La demi-vie du modafinil est d'environ huit Г douze heures dans la population gГ©nГ©rale.
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