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Modiodal Drogue
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Modiodal Drogue
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Il a Г©galement Г©tГ© utilisГ© pour amГ©liorer la cognition chez les personnes prГ©sentant des dГ©ficits, Г la fois chez les personnes atteintes d'un trouble dГ©ficitaire de l'attention avec hyperactivitГ© (TDAH) et chez les personnes ГўgГ©es. Le modafinil figure sur la liste des interdictions de l'Agence mondiale antidopage en tant qu'agent dopant et mГ©dicament amГ©liorant la performance, et est associГ© Г une augmentation du risque d'Г©vГ©nements cardiovasculaires. Les enzymes CYP1A2 et 3A4 ont des rГґles mineurs. Le modafinil amГ©liore Г©galement l'Г©veil et augmente le temps passГ© Г©veillГ©. Le modafinil pourrait Г©galement ГЄtre utile dans le traitement d'une affection appelГ©e hypersomnie ; cependant, il n'est pas approuvГ© pour cette utilisation. La dose peut ГЄtre fractionnГ©e au cours d'une journГ©e. Le modafinil (nom de marque commun Provigil) est approuvГ© pour le traitement des troubles du sommeil liГ©s au travail postГ©, de la somnolence associГ©e Г l'apnГ©e obstructive du sommeil et de la narcolepsie, ainsi que pour ГЄtre utilisГ© comme mГ©dicament amГ©liorant les performances par ceux qui cherchent Г amГ©liorer leur fonction cognitive. La demi-vie d'Г©limination est inversement proportionnelle au poids corporel. Le modafinil rГ©duit la somnolence diurne chez les personnes atteintes de certaines conditions mГ©dicales. Certaines personnes ne le prennent que lorsqu'elles se couchent, et certaines le prennent mГЄme pendant la journГ©e. Il est commercialisГ© dans plusieurs pays dans une variГ©tГ© de formulations. Modiodal Drogue Chez l'homme, le modafinil augmente l'Г©veil, augmente la durГ©e totale du sommeil et augmente la vigilance diurne, amГ©liore les mesures objectives et subjectives de la vigilance et de l'Г©veil, et amГ©liore les mesures neurophysiologiques de la vigilance. Il semble ГЄtre sГ»r et bien tolГ©rГ©. En outre, le modafinil a un effet positif chez les patients schizophrГЁnes ГўgГ©s, car il agit comme un activateur cognitif aidant Г l'apprentissage de l'environnement et du langage. Cela aide Г augmenter le flux sanguin et l'oxygГ©nation du cerveau. Chez les plus de 65 ans, il y a 4 demi-vies. Il est Г©galement utilisГ© pour traiter la somnolence excessive causГ©e par le travail postГ© ainsi que l'apnГ©e obstructive du sommeil. Le modafinil, comme d'autres stimulants, agit sur le SNC en augmentant la quantitГ© d'adГ©nosine monophosphate cyclique (AMPc). Le modafinil pourrait Г©galement ГЄtre utile dans le traitement d'une affection appelГ©e hypersomnie ; cependant, il n'est pas approuvГ© pour cette utilisation. Si la dose a Г©tГ© efficace, la dose quotidienne peut ГЄtre progressivement augmentГ©e jusqu'Г 300 mg. Il est peu probable que les gens deviennent dГ©pendants. Modafinil s'appelait Г l'origine R 948 en France.
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