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Provigil En Maroc
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Le modafinil est disponible en pilules ou gélules. Il est conçu pour aider le cerveau à réagir à la fatigue mentale. Cette étude a été publiée dans le Actes de l'Académie nationale des sciences des États-Unis d'Amérique. Il est disponible au Royaume-Uni en tant que médicament générique et en tant que médicament délivré uniquement sur ordonnance dans de nombreux autres pays. Bien que l'effet soit généralement d'un niveau modéré, l'amélioration peut être suffisante pour permettre aux travailleurs d'effectuer plus de travail en une seule journée. Provigil En Maroc Le fabricant suggère de prendre du modafinil entre 3 et 6 heures avant le coucher. Il a été breveté en 1972 et approuvé aux États-Unis en 1994. D'autres effets peuvent inclure une diminution de l'appétit, une diminution de la tension artérielle et une augmentation des sensations d'énergie physique ou d'excitation. La clairance du modafinil et du N-desméthylmodafinil diffère selon le génotype CYP2C19, de sorte que les individus homozygotes pour le génotype CYP2C19*1*1 ont une clairance significativement plus faible du modafinil, par rapport aux hétérozygotes CYP2C19*1*2 ou aux homozygotes CYP2C19*1*3 (40 % contre. Le modafinil exerce des effets similaires chez les animaux de laboratoire et les humains. Les effets secondaires, le cas échéant, dépendront de la quantité prise. Ces médicaments peuvent augmenter les niveaux de modafinil. Dans les cas plus graves, une dose de 300 mg peut être prise initialement, avec des ajustements posologiques à la hausse après trois à quatre jours. Le modafinil est un agoniste inverse partiel du complexe récepteur GABAA. Il est utilisé pour traiter la somnolence dans la narcolepsie. Le modafinil n'a pas été approuvé pour une utilisation dans le traitement de la schizophrénie. Le modafinil réduit la transmission des catécholamines, y compris l'activation de l'amygdale, chez l'homme.
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