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modafinil belgique
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modafinil belgique
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Le modafinil inhibe en fait l'activitГ© du cervelet, qui contrГґle la somnolence. Les femmes enceintes ou allaitantes ne doivent pas l'utiliser. Comme avec tous les mГ©dicaments, les gens peuvent devenir allergiques au modafinil, avec une variГ©tГ© de symptГґmes allant de l'urticaire et des Г©ruptions cutanГ©es, Г des difficultГ©s respiratoires et Г une lГ©thargie extrГЄme. Certaines Г©tudes ont suggГ©rГ© que le modafinil amГ©liore l'attention, la mГ©moire et l'humeur. Chez les personnes ГўgГ©es, on a constatГ© qu'il Г©tait absorbГ© plus lentement et qu'il avait une demi-vie plus longue, prenant 2 Г 3 jours pour atteindre un niveau plasmatique maximal. Selon des Г©tudes mГ©dicales, le modafinil est gГ©nГ©ralement efficace pendant au moins deux Г trois nuits aprГЁs l'administration, mais ne semble pas empГЄcher le besoin de dormir aprГЁs environ cinq nuits. Dans des Г©tudes animales, les scientifiques ont dГ©couvert que le modafinil augmente le temps que les rongeurs passent Г©veillГ©s et augmente le temps passГ© dans des Г©tats actifs, affectant ainsi le cycle circadien. Le modafinil est disponible sous forme d'alphachlorГ©thyl (oral ou Provigil Ultra 100 mg) et de sibutramine (poudre redispersable). La dose adulte recommandГ©e est de 100 Г 200 mg. Il appartient Г un groupe de mГ©dicaments appelГ©s psychostimulants. Effets: Le modafinil augmente l'Г©veil, amГ©liore la vigilance, la concentration et la mГ©moire. Le modafinil est principalement utilisГ© pour traiter la somnolence excessive associГ©e Г la narcolepsie, la somnolence causГ©e par le travail postГ© et pour amГ©liorer l'Г©veil des personnes souffrant d'apnГ©e obstructive du sommeil. Le modafinil est un dГ©rivГ© du biphГ©nyle qui agit comme un inhibiteur sГ©lectif et rГ©versible de la recapture des neurotransmetteurs dopamine et noradrГ©naline. La demi-vie du modafinil est d'environ 17 heures. modafinil belgique Le modafinil est disponible sous forme de patch transdermique, de pilule Г libГ©ration prolongГ©e et de capsule contenant 120 mg. Le modafinil est composГ© de deux substances : le R-modafinil, l'Г©nantiomГЁre actif ® et un Г©nantiomГЁre inactif (S). Il est disponible en dose fixe de 100 mg, 200 mg et 400 mg. Le mГ©canisme prГ©cis n'est pas clair, mais certaines recherches ont suggГ©rГ© que le Modafinil pourrait agir par l'activation des rГ©cepteurs adrГ©nergiques dans le cerveau. Cependant, les personnes ayant des antГ©cГ©dents d'abus peuvent s'habituer aux effets. Il est commercialisГ© sous diverses marques, notamment Armodafinil, Armodafinil R, Armodafinil XP, Modavigil et Modavigil Forte. Il s'agit d'un mГ©lange racГ©mique de deux stГ©rГ©oisomГЁres, le R-modafinil et le S-modafinil, qui sont formГ©s dans le corps Г partir de la mГЄme molГ©cule de dГ©part mais qui diffГЁrent par leur forme et leurs propriГ©tГ©s. C'est Г©galement un traitement de classe 1 pour le trouble dГ©ficitaire de l'attention avec hyperactivitГ© (TDAH). Le modafinil augmente Г©galement le dГ©clenchement du systГЁme cholinergique dans le cerveau antГ©rieur basal via l'inhibition de l'acГ©tylcholinestГ©rase et la potentialisation du nombre de rГ©cepteurs nicotiniques au niveau des sites postsynaptiques. Le modafinil est capable de prolonger la durГ©e de l'Г©veil. Ces sels sont appelГ©s modafinil. Les utilisations approuvГ©es sont pour traiter la somnolence liГ©e au travail postГ© et comme traitement d'entretien pour les patients. Le modafinil est un dГ©rivГ© de la benzodiazГ©pine.
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